Schwartz Pediatric Bedside eGFR (2009)

The revised "bedside" pediatric eGFR requires only serum creatinine and height.

About

The original Schwartz eGFR formula was devised in the mid-1970s to estimate GFR in children. This model was felt to overestimates GFR, likely a result of a change in methods used to measure creatinine.

In 2009, Schwartz et al developed a revised estimated GFR formula using data from cohort of children in the Chronic Kidney Disease in Children (CKiD) study.

This model is appropriate for children between the ages of 1 to 16 yr.

The linear regression analyses generated a model that included the following:

  • height (meters)
  • serum creatinine (mg/dL)
  • cystatin C (mg/L)
  • Blood urea nitrogen (mg/dL)
  • Gender

The full equation is as follows:

  • GFR (ml/min per 1.73 m2) =
  • 39.1[height/creatinine]0.516 X [1.8/cystatin C]0.294 [30/BUN]0.169 [1.099]male [height/1.4]0.188

Given the complexity of this formula, a "bedside" version requiring only height and creatinine was developed:

eGFR = 0.413 X (height/serum creatinine),
where height is in cm, and creatinine is in mg/dL

References

Schwartz GJ, Muñoz A, Schneider MF, Mak RH, Kaskel F, Warady BA, Furth SL.

Journal of the American Society of Nephrology: JASN 2009, 20 (3): 629-37

The Schwartz Pediatric Bedside eGFR (2009) calculator is created by QxMD.

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1. Creatinine?

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