San Francisco Syncope Rule
Identify those at low risk of adverse outcome after a syncopal episode
The San Francisco Syncope rule identifies patients who cannot be considered low risk of adverse outcomes after a syncopal event.
- History of congestive heart failure
- Hematocrit <30%
- Abnormal EKG (New ECG change from any source, any non-sinus rhythm on EKG or monitoring)
- Symptoms of shortness of breath
- Systolic BP <90 mmHg at triage
If any of these criteria are noted, patient cannot be considered "low risk" of a serious outcome. In this study, a serious outcome is defined as "death, myocardial infarction, arrhythmia, pulmonary embolism, stroke, subarachnoid hemorrhage, significant hemorrhage, or any condition causing a return ED visit and hospitalization for a related event."
While the original paper identified a 96% sensitivity and 62% specificity for serious outcome (with negative predictive value 99.2% and positive predictive value 24.8%), validation studies have reported inconsistent results.
Quinn J, McDermott D, Stiell I, Kohn M, Wells G.
Annals of Emergency Medicine 2006, 47 (5): 448-54
Birnbaum A, Esses D, Bijur P, Wollowitz A, Gallagher EJ.
Annals of Emergency Medicine 2008, 52 (2): 151-9
The San Francisco Syncope Rule calculator is created by QxMD.