PEN-FAST - Penicillin Allergy Risk Tool

Clinical decision rule for point-of-care risk assessment of patient-reported penicillin allergies.

About

The PEN-FAST penicillin allergy clinical decision rule enables point-of-care risk assessment of patient-reported penicillin allergies. It requires three clinical criteria:

  • Time (five years or less) from penicillin allergy episode (2 points)
  • Phenotype (anaphylaxis/angioedema OR SCAR) (2 points)
  • Treatment required for penicillin allergy episode (1 point)

The risk of a positive penicillin allergy test can be accurately predicted from these criteria:

  • 0 points – Very low risk of positive penicillin allergy test <1%
  • 1-2 points – Low risk of positive penicillin allergy test 5%
  • 3 points – Moderate risk of positive penicillin allergy test 20%
  • 4 points – High risk of positive penicillin allergy test 50%

References

Trubiano JA, Vogrin S, Chua KYL et al.

Development and Validation of a Penicillin Allergy Clinical Decision Rule.

JAMA Internal Med. Published March 16, 2020. doi:10.1001/jamainternmed.2020.0403

The PEN-FAST - Penicillin Allergy Risk Tool calculator is created by QxMD.

Created by on 26/05/2020

By using this site you acknowledge that you have read, understand, and agree to be bound by our terms of use and privacy policy. All content and tools are for educational use only, are not meant to be a substitute for professional advice and should not be used for medical diagnosis and/or medical treatment.

1. PEN - Penicillin allergy reported by patient

More Information

Only patients who report a penicillin allergy are eligible for PEN-FAST.

0/5 completed