ADEQUACY AND ULTRAFILTRATION GOALS

  • The minimum delivered weekly Kt/Vurea of 1.7 represents peritoneal clearance alone or peritoneal plus renal clearance1
  • While the Kidney Disease Outcomes Quality Initiative (KDOQI) guidelines do not recommend use of creatinine clearance to assess adequacy, creatinine clearance goals of 45 L/wk in APD patients are advocated by the International Society of Peritoneal Dialysis (ISPD) and other organizations1-6
  • Euvolemia is critical to improve patient outcomes1
  • While no recommendation regarding an ultrafiltration (UF) target exists in the United States, other countries recommend an arbitrary UF target of 750–1000 mL/day in anuric patients, based upon improved outcomes in observational studies4, 5, 7

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